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HPLC's
strength lies in its versatility, sensitivity, and selectivity. This chromatographic
technique uses different mobile phases and columns to achieve the
necessary separation of polar, thermally labile, non-volatile and other analytes that cannot
be analyzed by gas chromatography. HPLC is non-destructive and analytes
can be isolated for further spectroscopic analysis. Very low detection
levels are achievable and multiple detectors can be used in series to monitor
specific analytes. A wide variety of detectors are used in this laboratory
to determine electrochemically active compounds, high molecular weight
analytes, and non-UV absorbing materials.

- Quantification
and identification of inhibitors and other electrochemically active components in products.
- Trace analysis of polymeric extracts
- Characterization
of isocyanates, sulfonic acids, biocides, and peroxides through the
application of derivatization techniques, ion pairing, normal and reversed-phase HPLC.
- Quantification
of glycols at low levels in aqueous systems using pulsed-mode amperometry (PAD).
- Isolation
of specific analytes for further spectroscopic analysis and use of preparative
LC columns permits simultaneous analysis and trapping.
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